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Wiki Education Foundation-supported course assignment[edit]

This article is or was the subject of a Wiki Education Foundation-supported course assignment. Further details are available on the course page. Student editor(s): Jatakaki, Superbug24.

Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT (talk) 02:45, 17 January 2022 (UTC)[reply]


Some sections have been taken word-for-word from www.chemistrydaily.com Chemmaj 18:34, 6 July 2007 (UTC)[reply]

hi i am a 53 year old extremly overweight female with 11 yrs of steriod use. i had severe pain in my stomach and went to the emergy room, the doctor did a ultra sound a said my liver was very in larged, it was about 5-6 ins and was from my diafram to almost my waist line. He ordered liver panel test i told him my PPC had just did a liver panel about 3-4 month ago and it was normal. Anyways the test came back ok, and he just dropped the issue of the enlarged liver. Should i be concerned?


Wikipedia does not give medical advice, it simply documents the state of medical practice. If you have any further concerns, your physician is the first person to speak to. JFW | T@lk 14:58, 2 September 2005 (UTC)[reply]


I've moved AST into the regular liver panel. Agreed that it is less liver specific, but I think it's considered part of a typical liver profile, and the AST:ALT is quite useful in diagnostics. Samir धर्म 08:21, 26 January 2006 (UTC)[reply]

Home Testing Kits[edit]

I feel it is definately worth mentioning the news story and subsequent multitude of home testing liver kits. —Preceding unsigned comment added by (talk) 01:03, 13 November 2009 (UTC)[reply]

Alkaline phosphatase: AP or ALP?[edit]

This page abbreviates it as AP, but other pages use ALP, as does my own doctor's lab. Is there a standard? --User: Karn 0355 UTC 24 Feb 2006.

It is more usually ALP, I would support a change if that is what you are proposing Ianmc 21:09, 24 February 2006 (UTC)[reply]

I'd support a change back to ALP too. It was recently changed by one anon without comment. Tristanb 19:01, 8 March 2006 (UTC)[reply]

ALP it should be. JFW | T@lk 21:19, 8 March 2006 (UTC)[reply]

ALP is more common in UK usage in my experience (also AlkPhos) David Ruben Talk 00:33, 9 March 2006 (UTC)[reply]

I've changed it back to ALP, I don't think the anon will re-alter it. Tristanb 07:37, 12 March 2006 (UTC)[reply]

No need for doctors?[edit]

I deleted the reference to the end users of LFTs as unecessary based on this discussion with Ravn. Lots of people use LFTs outside of healthcare professionals, patients and lawyers to name but two. Ianmc 01:18, 8 March 2006 (UTC)[reply]


Technically liver function tests are albumin, INR, bilirubin, glucose and factors save VIII. Liver enzymes are AST, ALT, ALP, GGT and 5'NTD. Is this the common understanding, and should the article be factored as such? -- Samir धर्म 09:19, 31 May 2006 (UTC)[reply]

Here in UK, requesting LFTs would generaly yield Bilirubin, ALP, AST or ALT, sometimes gGT, Total Protein, Albumin, sometimes Globulin. Some hospitals do not offer gGT as a routine (cost cutting measure) but only on specific request. Glucose seems only very occasionally included (given that better to specifically request a faster glucose level if really required). I agree coagulation tests part of assessing overall liver status, but never seen as part of LFTs (indeed tests are undertaken by a different lab - haematology - rather than Biochemistry (aka Chemical Pathology) for the LFTs. David Ruben Talk 09:51, 31 May 2006 (UTC)[reply]
I would not wish to imply though that Liver function tests should be a separate article from LFTs - distinction is too fine for a general encyclopaedia and the one article could & should be able to clarify any differences better than spliting the topics in two. David Ruben Talk 12:33, 31 May 2006 (UTC)[reply]
In specialty hepatology, I think the term "LFT" has gone completely out of favour for this reason. -- Samir धर्म 17:32, 31 May 2006 (UTC)[reply]
The distinction between liver panel, LFTs, liver enzymes, and true tests of liver function are emphasized at my medical school and its teaching hospitals. "Liver panel" is generally the preferred term here because it doesn't mislabel ALP and the transaminases as tests of liver function. Despite this preferred usage, however, "liver panel" and "LFTs" are thrown around as synonyms, and there's no assumption that when one requests LFTs, they are truly asking for albumin, INR, glucose, bilirubin, etc. A pity for pedants like me; and my attendings too, who tend to give the poor intern a hard time for ever having uttered the word "function" in the first place. :-) Anyhow, I think this distinction is best handled in the article by indicating that "liver function tests" traditionally include ALP, AST, ALT, and bilirubin, but that the term "function" is a misnomer. These classic LFTs are indicators of hepatic injury, not tests of its synthetic or metabolic functions. A separate section on true tests of liver function can address the INR, albumin, etc. --David Iberri (talk) 12:28, 18 February 2009 (UTC)[reply]

There should be a separate article for LFTs. AST/ALT have nothing to do here. 2607:FA48:6D3B:3F0:85C7:C91E:E7A2:5123 (talk) 10:13, 24 May 2013 (UTC) louism[reply]


the word transaminasemia appears nowhere in wikipedia and should. Is this article able to incorporate the word? (talk) 21:32, 2 June 2008 (UTC)[reply]

Transaminasemia best belongs as a redirect to Elevated transaminases. --David Iberri (talk) 12:32, 18 February 2009 (UTC)[reply]

Reduced Liver enzymes?[edit]

The article correctly addresses the conditions that may be manifesting with elevated liver enzymes resulting from liver damage. However, I haven't noticed anything discussing reduced liver enzymes and their clinical significance. Some liver enzymes are kept within a specific range but the article discusses only the clinical significance of these enzymes when they appear elevated.


I know ammonia level is not part of your usual Liver Profile tests but is a very specific test for determining liver function since the liver is responsible to convert this highly toxic body waste into the far more innocuous urea. Opinions?... Learningnave (talk) 10:03, 7 April 2013 (UTC)[reply]

Possible vandalism: "A2"[edit]

I've reverted addition of the following by unregistered user as possible vandalism:

Test result A2 means patient having minor damage.

By itself, this is nonconstructive. If it had a legitimate purpose, please explain the context and meaning of the code "A2", and provide a source, rather than just adding back the sentence by itself. Also, even if legitimate, it probably does not belong in the lead paragraph.

Syrenka V (talk) 17:52, 17 March 2018 (UTC)[reply]

Liver Failure[edit]

Trazadone caused my liver to fail and disrupted 6.5 years of my life. Doctors don’t understand the correlation so be wary and informed. 2600:4040:11EE:8000:4135:53E0:5E2F:50B7 (talk) 23:01, 18 November 2021 (UTC)[reply]